Presenter Information

Dustin Bales, University of Wyoming

Department

Mechanical Engineering

First Advisor

Dr. Carl Frick

Description

The purpose of this research was to investigate fatigue behavior of open cell porous scaffolds constructed of Polyparaphenylene (PPP). PPP is reputed to have strength and stiffness properties nearly an order of magnitude higher than conventional biomedical polymers, and is in compliance with biocompatibility standard ISO 10993. It is our belief that the exceptional strength, stiffness, and toughness of PPP will allow for the creation of a porous structure that can match the stiffness of trabecular bone, whi le maintaining suitable mechanical properties for use as a load - bearing biomaterial. Porous orthopedic biomaterials are advantageous because they offer the possibility of creating a strong interface through osteointegration (i.e. bone ingrowth). However, t he fatigue behavior (i.e. mechanical behavior under cyclic or repeated loading) of PPP has not been previously investigated, and would be critical for any such device. PPP samples of 75% porosity, with pore sizes appropriate for osteointegration, were cyc lically loaded until failure. Loading results were analyzed using well established foam theory, and were used to develop the relation between stress and the number of cycles to failure (S - N).

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Mechanical Behavior of Cyclically Loaded Polyparaphenylene Porous Scaffolds for P otential Use in Biomedical Devices

The purpose of this research was to investigate fatigue behavior of open cell porous scaffolds constructed of Polyparaphenylene (PPP). PPP is reputed to have strength and stiffness properties nearly an order of magnitude higher than conventional biomedical polymers, and is in compliance with biocompatibility standard ISO 10993. It is our belief that the exceptional strength, stiffness, and toughness of PPP will allow for the creation of a porous structure that can match the stiffness of trabecular bone, whi le maintaining suitable mechanical properties for use as a load - bearing biomaterial. Porous orthopedic biomaterials are advantageous because they offer the possibility of creating a strong interface through osteointegration (i.e. bone ingrowth). However, t he fatigue behavior (i.e. mechanical behavior under cyclic or repeated loading) of PPP has not been previously investigated, and would be critical for any such device. PPP samples of 75% porosity, with pore sizes appropriate for osteointegration, were cyc lically loaded until failure. Loading results were analyzed using well established foam theory, and were used to develop the relation between stress and the number of cycles to failure (S - N).