Presenter Information

Jacob Berg, University of Wyoming

Department

Department of Veterinary Sciences

First Advisor

Dr. Jeffery Adamovicz

Description

Bovine in the Greater Yellowstone Area (GYA) of the United States are consistently exposed to Brucella abortus. This bacterium has b een known to cause abortions in cattle resulting in an economic loss to the owner and operator. The current veterinary vaccine, B. abortus RB51, is inadequate in giving broad host range protection against infection in domestic livestock. A complete underst anding of how the vaccine strain, RB51 when given in a single dose, affects the immune response of cattle, Bos taurus . We propose to study the effects of multiple doses of RB51 in cattle. This study focuses on the methods needed to continue this research a nd move toward quantifying the results of vaccination of cattle against the Brucella abortus . This is a presentation of the methods developed to aid in that study.

Comments

Oral Presentation, NASA Space Grant Undergraduate Research Fellowship

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Methods in Immunology for Brucella Abortus

Bovine in the Greater Yellowstone Area (GYA) of the United States are consistently exposed to Brucella abortus. This bacterium has b een known to cause abortions in cattle resulting in an economic loss to the owner and operator. The current veterinary vaccine, B. abortus RB51, is inadequate in giving broad host range protection against infection in domestic livestock. A complete underst anding of how the vaccine strain, RB51 when given in a single dose, affects the immune response of cattle, Bos taurus . We propose to study the effects of multiple doses of RB51 in cattle. This study focuses on the methods needed to continue this research a nd move toward quantifying the results of vaccination of cattle against the Brucella abortus . This is a presentation of the methods developed to aid in that study.